Tsuno Study Reveals Rice Magnesium's Unique Gradual, Sustained Absorption Profile

Tsuno Rice Fine Chemicals has released findings from a human clinical study showing its rice bran-derived ingredient, "Rice Magnesium," absorbs gradually and keeps blood magnesium levels elevated for several hours. Business Wire reported the announcement on June 4, 2026. Unlike common magnesium supplements, which spike quickly and fade, this ingredient stays in the bloodstream longer without the digestive side effects that often come with standard pills.
The company plans to use these findings to push Rice Magnesium into global markets, including the United States, where the magnesium supplement category was worth $1.72 billion in 2026. Tsuno sees strong demand from pregnant women, athletes, and people with sleep problems — groups that need steady magnesium levels, not a quick spike.
Most magnesium supplements — like magnesium oxide or magnesium citrate — hit the bloodstream fast and leave just as fast. That rapid flush often acts like a mild laxative, a well-known complaint among users. Tsuno's study compared Rice Magnesium directly against these common forms. The rice-derived version entered the blood slowly and stayed elevated for several hours, according to Business Wire.
An earlier rat study published by Gavin Publishers in 2016 pointed toward the same pattern — stable blood levels for up to 12 hours. The plant-based matrix of rice bran appears to slow down how the body processes the magnesium, keeping more of it available for longer. Tsuno says urinary elimination — how fast the body flushes it out — was also lower than with some competing forms.
Tsuno Rice Fine Chemicals was founded in 1972 specifically to find value in rice bran, a byproduct of milling that was largely thrown away. The Tsuno Group itself dates back to 1947, when founder Masatsugu Tsukino opened a wheat mill in Japan. The company has spent decades pulling functional ingredients — like ferulic acid and magnesium — out of material most processors discarded.
Rice bran naturally contains high concentrations of magnesium phosphate. Tsuno uses proprietary refining processes to concentrate this into Rice Magnesium, a plant-based alternative to mineral-derived supplements. Japan's Ministry of Health confirmed in its 2024 National Health and Nutrition Survey that magnesium deficiency remains widespread across the Japanese population, setting a clear domestic need for better options.
Tsuno is targeting three specific groups with this ingredient. Pregnant women need more magnesium but often experience constipation from traditional supplements. Rice Magnesium's gentler absorption could give prenatal products a meaningful edge. Endurance athletes — runners and cyclists — need magnesium to manage muscle fatigue over long efforts, where a sustained release matters more than a single spike.
The third target is sleep. Magnesium helps the body stay asleep, not just fall asleep. A supplement that fades after two hours does little for someone waking at 3 a.m. Tsuno argues that sustained blood levels through the night directly addresses "maintenance insomnia" — a growing segment of the sleep health market. The company already exports to Taiwan, South Korea, and Europe, with the US next in line.
Not everyone is convinced that a plant-based, sustained-release form justifies a higher price tag. Magnesium oxide remains the cheapest option per milligram, and some researchers argue that when a person's magnesium stores are already full, the specific form makes little difference to long-term health. A 2017 study in Food and Nutrition Research suggested that source type matters less than total daily intake for most people.
Tsuno also faces stiff competition from magnesium bisglycinate, a chelated form that marketers promote for neurological and stress benefits. The rice bran ingredient must compete not just on how long it absorbs, but on specific health claims. The global rice bran derivatives market was valued at $7.62 billion in 2025 and is projected to hit $12.44 billion by 2034, according to market research reports — giving Tsuno a rising tide, but also more crowded competition.
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